Myofascial pain syndrome is a debilitating disease of the muscles in which pain radiates from one or more trigger points that may be present in all muscles, and in many muscles at the same time, whether stimulated with pressure or not. Symptoms of myofascial pain syndrome include: throbbing pain, small and painful knots in the muscles, reduced range of motion, muscle soreness or tenderness and muscle weakness, headaches, poor sleep, fatigue, stress, anxiety and or depression. Although often confused with fibromyalgia, they are not the same.